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1

Epigenetische Therapie bei Myelodysplastischen Syndromen (MDS). Therapie mit DNA-Methyltransferase-Inhibitoren

Michael Daskalakis, Nadja Blagitko-Dorfs, Björn Hackanson, Michael Lübbert

Journal:

Pharmazie in unserer Zeit

Year:

2010

Language:

german

File:

PDF, 429 KB

german, 2010

2

Epigenetic Priming of AML Blasts for All-trans Retinoic Acid-Induced Differentiation by the HDAC Class-I Selective Inhibitor Entinostat

Blagitko-Dorfs, Nadja, Jiang, Yi, Duque-Afonso, Jesús, Hiller, Jan, Yalcin, Arzu, Greve, Gabriele, Abdelkarim, Mahmoud, Hackanson, Björn, Lübbert, Michael, Lausen, Jörn

Journal:

Year:

2013

Language:

english

File:

PDF, 1.07 MB

english, 2013

3

The Silence of the Genes: Epigenetic Disturbances in Haematopoietic Malignancies

Bjoern Hackanson, Yalin Guo, Michael Luebbert

Journal:

Year:

2005

File:

PDF, 8 KB

2005

4

In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies

Björn Hackanson, Christian Robbel, Pierre Wijermans, Michael Lübbert

Journal:

Annals of Hematology

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

5

Long-term follow-up of patients with chronic myeloid leukemia having received autologous stem cell transplantation

Björn Hackanson, Cornelius F. Waller

Journal:

Annals of Hematology

Year:

2011

Language:

english

File:

PDF, 209 KB

english, 2011

6

Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy

Julia M. Wagner, Björn Hackanson, Michael Lübbert, Manfred Jung

Journal:

Clinical Epigenetics

Year:

2010

Language:

english

File:

PDF, 359 KB

english, 2010

7

Fatal varicella zoster virus encephalitis in two patients following allogeneic hematopoietic stem cell transplantation

Björn Hackanson, Robert Zeiser, Thorsten A Bley, Georgios Pantazis, Daniela Huzly, Hartmut Bertz, Jürgen Finke

Journal:

Clinical Transplantation

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

8

JC virus myelitis without cerebral involvement in acute myeloid leukemia

O. Stich, M. Herpers, A. Keil, B. Hackanson, K. Damjanovic, S. Meckel, S. Rauer

Journal:

European Journal of Neurology

Year:

2011

Language:

english

File:

PDF, 114 KB

english, 2011

9

NHR4 domain mutations of ETO are probably very infrequent in AML1–ETO positive myeloid leukemia cells

Hackanson, B, Abdelkarim, M, Jansen, J H, Lübbert, M

Journal:

Year:

2010

Language:

english

File:

PDF, 140 KB

english, 2010

10

TSC-22 contributes to hematopoietic precursor cell proliferation and repopulation and is epigenetically silenced in large granular lymphocyte leukemia

Yu, J., Ershler, M., Yu, L., Wei, M., Hackanson, B., Yokohama, A., Mitsui, T., Liu, C., Mao, H., Liu, S.

Journal:

Year:

2009

Language:

english

File:

PDF, 605 KB

english, 2009

11

Quantitative analyses of DAPK1 methylation in AML and MDS

Rainer Claus, Björn Hackanson, Anna R. Poetsch, Manuela Zucknick, Miriam Sonnet, Nadja Blagitko-Dorfs, Jan Hiller, Stefan Wilop, Tim H. Brümmendorf, Oliver Galm, Uwe Platzbecker, John C. Byrd, Konstan

Journal:

International Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 240 KB

english, 2012

12

HDAC6 as a target for antileukemic drugs in acute myeloid leukemia

Björn Hackanson, Leander Rimmele, Marco Benkißer, Mahmoud Abdelkarim, Manfred Fliegauf, Manfred Jung, Michael Lübbert

Journal:

Leukemia Research

Year:

2012

Language:

english

File:

PDF, 1.16 MB

english, 2012

13

Hyperleukocytotic secondary acute myeloid leukemia (AML) with sole monosomy 7 as sequela of Philadelphia-chromosome positive chronic myeloid leukemia (CML)

Björn Hackanson, Anja Rückert, Michael Lübbert

Journal:

European Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 106 KB

english, 2009

14

Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia

Aparna Raval, Stephan M. Tanner, John C. Byrd, Elizabeth B. Angerman, James D. Perko, Shih-Shih Chen, Björn Hackanson, Michael R. Grever, David M. Lucas, Jennifer J. Matkovic, Thomas S. Lin, Thomas J.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.45 MB

english, 2007

15

MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells

Arzu Yalcin, Clemens Kreutz, Dietmar Pfeifer, Mahmoud Abdelkarim, Gregor Klaus, Jens Timmer, Michael Lübbert, Björn Hackanson

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

16

Decitabine induces very early in vivo DNA methylation changes in blasts from patients with acute myeloid leukemia

Claus, Rainer, Pfeifer, Dietmar, Almstedt, Maika, Zucknick, Manuela, Hackanson, Björn, Plass, Christoph, Lübbert, Michael

Journal:

Leukemia Research

Year:

2013

Language:

english

File:

PDF, 662 KB

english, 2013

17

Tracing the development of acute myeloid leukemia in CBL syndrome

Becker, H., Yoshida, K., Blagitko-Dorfs, N., Claus, R., Pantic, M., Abdelkarim, M., Niemoller, C., Greil, C., Hackanson, B., Shiraishi, Y., Chiba, K., Tanaka, H., Miyano, S., Dohner, K., Schnittger, S

Journal:

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

18

BM cells giving rise to MSC in culture have a heterogeneous CD34 and CD45 phenotype

Kaiser, S., Hackanson, B., Follo, M., Mehlhorn, A., Geiger, K., Ihorst, G., Kapp, U.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.25 MB

english, 2007

19

The silence of the genes: epigenetic disturbances in haematopoietic malignancies

Hackanson, Björn, Guo, Yalin, Lübbert, Michael

Journal:

Expert Opinion on Therapeutic Targets

Year:

2005

Language:

english

File:

PDF, 418 KB

english, 2005

20

Epigenetic Modulation of Tumor Suppressor CCAAT/Enhancer Binding Protein Activity in Lung Cancer

Tada, Y., Brena, R. M., Hackanson, B., Morrison, C., Otterson, G. A., Plass, C.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2006

Language:

english

File:

PDF, 1.12 MB

english, 2006

21

[IEEE EQEC '05. European Quantum Electronics Conference, 2005. - Munich, Germany (12-17 June 2005)] EQEC '05. European Quantum Electronics Conference, 2005. - Influencing a single fluorescent molecule with single metallic nanoparticle

Kuhn, S., Hackanson, U., Rogobete, L., Sandoghdar, V.

Year:

2005

Language:

english

File:

PDF, 576 KB

english, 2005

22

XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors

Hackanson, B., Becker, H., Berg, T., Binder, M., Dierks, C., Duque-Afonso, J., Lairmore, M. D., Schafer, H. S., Schnitzler, M., Zeiser, R., Martens, U., Mertelsmann, R., Lubbert, M.

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 218 KB

english, 2008

23

Epigenetic Modification of CCAAT/Enhancer Binding Protein Expression in Acute Myeloid Leukemia

Hackanson, B., Bennett, K. L., Brena, R. M., Jiang, J., Claus, R., Chen, S.-S., Blagitko-Dorfs, N., Maharry, K., Whitman, S. P., Schmittgen, T. D., Lubbert, M., Marcucci, G., Bloomfield, C. D., Plass,

Journal:

Cancer Research

Year:

2008

Language:

english

File:

PDF, 776 KB

english, 2008

24

Unusual Cases in Multiple Myeloma and a Dramatic Response in Metastatic Lung Cancer: CASE 1. Multiple Myeloma Relapse Presenting As Malignant Pericardial Effusion

Zeiser, R., Hackanson, B., Bley, T. A., Finke, J., Bertz, H.

Journal:

Journal of Clinical Oncology

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

25

Phase I Study of Decitabine Alone or in Combination With Valproic Acid in Acute Myeloid Leukemia

Blum, W., Klisovic, R. B., Hackanson, B., Liu, Z., Liu, S., Devine, H., Vukosavljevic, T., Huynh, L., Lozanski, G., Kefauver, C., Plass, C., Devine, S. M., Heerema, N. A., Murgo, A., Chan, K. K., Grev

Journal:

Journal of Clinical Oncology

Year:

2007

Language:

english

File:

PDF, 418 KB

english, 2007

26

A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy

Lubbert, M., Ruter, B. H., Claus, R., Schmoor, C., Schmid, M., Germing, U., Kuendgen, A., Rethwisch, V., Ganser, A., Platzbecker, U., Galm, O., Brugger, W., Heil, G., Hackanson, B., Deschler, B., Dohn

Journal:

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

27

DECIDER: prospective randomized multicenter phase II trial of low-dose decitabine (DAC) administered alone or in combination with the histone deacetylase inhibitor valproic acid (VPA) and all-trans retinoic acid (ATRA) in patients >60 years with acute myeloid leukemia who are ineligible for induction chemotherapy

Grishina, Olga, Schmoor, Claudia, Döhner, Konstanze, Hackanson, Björn, Lubrich, Beate, May, Annette M., Cieslik, Caroline, Müller, Michael J., Lübbert, Michael

Journal:

Year:

2015

Language:

english

File:

PDF, 1.43 MB

english, 2015

28

Tumor Suppressor Activity of CCAAT/Enhancer Binding Protein Is Epigenetically Down-regulated in Head and Neck Squamous Cell Carcinoma

Bennett, K. L., Hackanson, B., Smith, L. T., Morrison, C. D., Lang, J. C., Schuller, D. E., Weber, F., Eng, C., Plass, C.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 543 KB

english, 2007

29

Epigenetische Modifikationen in malignen Zellen

Hackanson, B., Lübbert, M.

Journal:

TumorDiagnostik & Therapie

Year:

2011

Language:

german

File:

PDF, 240 KB

german, 2011

30

Epigenetische Modifikationen in malignen Zellen

Hackanson, B, Lübbert, M

Journal:

DMW - Deutsche Medizinische Wochenschrift

Year:

2011

Language:

german

File:

PDF, 204 KB

german, 2011

31

Long-term follow-up of therapy-related myelodysplasia and AML patients treated with allogeneic hematopoietic cell transplantation

Finke, J, Schmoor, C, Bertz, H, Marks, R, Wäsch, R, Zeiser, R, Hackanson, B

Journal:

Bone Marrow Transplantation

Year:

2016

Language:

english

File:

PDF, 690 KB

english, 2016

32

Gene expression analysis of decitabine treated AML: high impact of tumor suppressor gene expression changes

Bohl, Stephan R., Dolnik, Anna, Jensen, Thomas, Lang, Katharina M., Hackanson, Björn, Gaidzik, Verena I., Paschka, Peter, Knudsen, Steen, Döhner, Konstanze, Döhner, Hartmut, Claus, Rainer, Lübbert, Mi

Journal:

Leukemia and Lymphoma

Year:

2017

Language:

english

File:

PDF, 971 KB

english, 2017

33

Tumor Cell Heterogeneity in Small Cell Lung Cancer (SCLC): Phenotypical and Functional Differences Associated with Epithelial-Mesenchymal Transition (EMT) and DNA Methylation Changes

Krohn, Alexander, Ahrens, Theresa, Yalcin, Arzu, Plönes, Till, Wehrle, Julius, Taromi, Sanaz, Wollner, Stefan, Follo, Marie, Brabletz, Thomas, Mani, Sendurai A., Claus, Rainer, Hackanson, Björn, Burge

Journal:

Year:

2014

Language:

english

File:

PDF, 3.00 MB

english, 2014

34

Molecular Genetic Characterization of Individual Cancer Cells Isolated via Single-Cell Printing

Riba, Julian, Renz, Nathalie, Niemöller, Christoph, Bleul, Sabine, Pfeifer, Dietmar, Stosch, Juliane M., Metzeler, Klaus H., Hackanson, Björn, Lübbert, Michael, Duyster, Justus, Koltay, Peter, Zengerl

Journal:

Year:

2016

Language:

english

File:

PDF, 2.88 MB

english, 2016

35

Patienten mit mNSCLC profitieren unabhängig von der PD-L1-Expression von einer PD-1-Blockade

Neumaier, Judith, Hackanson, Björn

Journal:

Im Focus Onkologie

Year:

2018

File:

PDF, 160 KB

2018

36

The clinical management of lenalidomide-based therapy in patients with newly diagnosed multiple myeloma

Merz, Maximilian, Dechow, Tobias, Scheytt, Mithun, Schmidt, Christian, Hackanson, Bjoern, Knop, Stefan

Journal:

Annals of Hematology

Year:

2020

File:

PDF, 512 KB

2020

37

Monosomal karyotype and chromosome 17p loss or TP53 mutations in decitabine-treated patients with acute myeloid leukemia

Becker, Heiko, Pfeifer, Dietmar, Ihorst, Gabriele, Pantic, Milena, Wehrle, Julius, RÃ¼ter, BjÃ¶rn H., Bullinger, Lars, Hackanson, BjÃ¶rn, Germing, Ulrich, Kuendgen, Andrea, Platzbecker, Uwe, DÃ¶hner,

Journal:

Annals of Hematology

Year:

2020

File:

PDF, 1.06 MB

2020

38

Phase Ib study of BI 836880, a VEGF/Ang2-blocking nanobodyÂ®, in combination with BI 754091, an anti-PD-1 antibody: Initial results in patients (pts) with solid tumours

Girard, N., Wermke, M., Barlesi, F., Kim, D-W., Ghiringhelli, F., Landsteiner, H.T., Jayadeva, G., Alt, J., Hackanson, B.

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 74 KB

2020

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